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ORAL COMMUNICATIONS

Thursday, June 15

9.00-11.00

C 1.Rectal motor and sensory function in different subtypes of constipation. C. Penning, J. Steens, P.J. van der Schaar, J.Ph. Kuyvenhoven, J.B.V.M. Delemarre, C.B.H.W. Lamers, A.A.M. Masclee. Depts. of Gastroenterology and Surgery, Leiden University Medical Center, Leiden (The Netherlands)

C 2.Rectal distension inhibits colonic tone and motility. J. Steens, J. Brussee, P.J. van der Schaar, A.A.M. Masclee. Dept. of Gastroenterology, Leiden University Medical Center, Leiden (The Netherlands)

C 3.Abnormal preprandial and postprandial sympathetic nerve activity in patients with irritable bowel syndrome. G.I. Andriesse, L.M.A. Akkermans, P. Schierek, G.H. Wieneke, P.L. Oey. Depts. of Surgery, Medical Physiology and Sports Medicine, and Clinical Neurophysiology, University Medical Center, Utrecht (The Netherlands)

C4.Dept. of Pharmacology, Gent University, Gent (Belgium)

C 5.Cholinergic 5-HT₄ receptor stimulation enhances canine and human colon longitudinal muscle contractility. N.H. Prins, L.M.A. Akkermans, R.A. Lefebvre, P. Cheyns, J.A.J. Schuurkes. Dept. of GI Pharmacology, Janssen Research Foundation, Beerse (Belgium)

C 6.Physical activity prevents intestinal gas retention. R. Dainese, J. Serra, F. Azpiroz, J-R. Malagelada.Digestive System Research Unit, Hospital Vall d'Hebron, Barcelona (Spain)

C 7.Psychological biases of non-painful rectal sensations in patients with irritable bowel. M. Corsetti, S. Bhoori, P.A. Bianchi, G. Basilisco. Cattedra di Gastroenterologia, Istituto di Scienze Mediche dell’Università, IRCCS-Ospedale Maggiore, Milano (Italy)

C 8.Somatic perception in irritable bowel syndrome (IBS) patients with and without fibromyalgia (FMS). Does the severity of IBS influence the perception of somatic stimuli? P. Iovino, E. Lubrano, F. Tremolaterra, E. Nirchio, F. Sabbatini, G. Mazzacca. Servizio di Endoscopia Digestiva, Fisiatria e Riabilitazione, Gastroenterologia, Università Federico II, Napoli (Italy)

ORAL COMMUNICATIONS

Thursday, June 15

15.00-16.30

C 9.Intracisternal injection of somatostatin receptor 5 agonists induces a vagal cholinergic stimulation of gastric emptying in rats. V. Martinez, Y. Taché. Dept. of Medicine and Brain Research Institute, UCLA, Los Angeles, CA (USA) Dept. of Physiology, CEU San Pablo, Veterinary School, Valencia (Spain)

C 10.Role of CRF receptors type 1 and 2 on peripheral urocortin-induced inhibition of food intake and gastric emptying in mice. V. Martinez, L. Wang, J. Rivier, Y. Taché. Dept. of Medicine and Brain Research Institute, UCLA, Los Angeles, CA (USA) The Salk Institute, La Jolla, CA (USA) Dept. of Physiology, CEU San Pablo, Veterinary School, Valencia (Spain)

C 11.Presynaptic modulation of cholinergic neurotransmission in the human gastric fundus. P.G. Leclere, R.A. Lefebvre. Heymans Institute of Pharmacology, Faculty of Medicine, Gent University, Gent (Belgium)

C 12.Murine myenteric neurons express dystrophin. M.G. Vannucchi, L. Corsani, M.S. Faussone-Pellegrini.Dept. of Anatomy, Histology and Forensic Medicine, University of Florence, Florence (Italy)

C 13.Interaction between NO and VIP in the gastric fundus of NOS knockout mice. J.M.C. Dick, W. Van Molle, R.A. Lefebvre. Heymans Institute of Pharmacology, Dept. of Molecular Biology, Gent University, Gent (Belgium)

C 14.Insulin modulates mechanosensitivity of duodenal vagal afferents. S. Blat, C.H. Malbert. Unité Mixte de Recherche sur le Veau et le Porc, INRA, Saint-Gilles (France)

ORAL COMMUNICATIONS

Friday, June 16

9.00-11.000

C 15.Calcium-dependent action potential generation in myenteric neurones of the rat oesophagus. A. De Laet, W. Cornelissen, P.-P. van Bogaert, D.W. Scheuermann, J.-P. Timmermans. Laboratory of Cell Biology and Histology, Laboratory of Electrobiology, University of Antwerp, Antwerp (Belgium)

C 16.Modulation of human swallowing motor cortex output following pharyngeal anaesthesia. C. Fraser, S. Hamdy, M. Power, J. Rothwell, D.G. Thompson. University Department of Gastroenterology , Hope Hospital, Manchester (UK) The Medical Research Council, Human Movement and Balance Unit, Insitute of Neurology, London (UK)

C 17.Perception of fear modulates the brain processing of human oesophageal sensation: a functional magnetic resonance imaging study. Q. Aziz, M.L. Phillips, L.J. Gregory, V. Ng, C. Andrews, A. Simmons, M. Brammer, A. Hobson, D.G. Thompson, S.C.R. Williams. Neuroimaging Research Group, Institute of Psychiatry, London (UK)   Department of Gastrointestinal Science, University of Manchester, Manchester (UK)

C 18.Repeated injections of botulinum toxin in achalasia do not induce tachyphilaxis. V. Annese, S. Fiorella, G. Lombardi, P. Conoscitore, N. Caruso, A. Andriulli. Division of Gastroenterology, CSS Hospital, San Giovanni Rotondo (Italy)

C 19.Liquid/gas components of duodeno-gastro-esophageal reflux during 24 hs ambulatory. Bilitec®-pH-impedance recordings in patients with reflux disease. D.A. Sifrim, R.H. Holloway, J. Tack, J. Silny, M. Trachterna, A. Lerut, J. Janssens. University of Leuven (Belgium), R. Adelaide Hospital (Australia), Helmholtz Institute (Germany)

C 20. Intragastric maldistribution in patients with reflux oesophagitis studied by an accurate 3D ultrasound system. S. Tefera, O.H. Gilja, E. Olafsdottir, T. Hausken, J.G. Hatlebakk, A. Berstad. Div. of Gastroenterology, Depts. of Medicine and Pediatrics, Haukeland University Hospital, Bergen (Norway).

C 21. Acid suppression enhances postprandial relaxation of the fundus in patients with functional dyspepsia. P.J. van der Schaar, C.B.H.W. Lamers, A.A.M. Masclee. Dept. of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden (The Netherlands).

C 22.Function of the proximal stomach after partial versus complete laparoscopic fundoplication. A.A.M. Masclee, M.Y.A. Lindeboom, M.K. Vu, P.J.J. van Rijn, P. Neijenhuis, J. Ringers. Depts. of Gastroenterology and Surgery, Leiden University Medical Center, Leiden (The Netherland).

ORAL COMMUNICATIONS

Friday, June 16

15.00-16.30

C 23.Acute restraint stress in female rats induces mast cells NK1 receptors activation in distal colon. S. Bradesi, H. Eutamene, V. Theodorou, J. Fioramonti, L. Bueno. Neurogastroenterology and Nutrition Unit, INRA, Toulouse (France)

C 24.The inhibitory effects of 5-HT agonists on the rabbit colon are reversed to excitatory effects by TNBS-colitis. I. Depoortere, T. Thijs, L. Thielemans, G. Van Assche, T.L. Peeters. Center for Gastroenterological Research, University of Leuven, Leuven (Belgium).

C 25. Effect of TNBS-Induced Ileitis on Relaxations of Non Inflamed Rat
Gastric Fundus. T.G. Moreels, JG. De Man, B.Y. De Winter, A.G. Herman & P.A.Pelckmans. Div. of Gastroenterology & Pharmacology, University of Antwerp, (UIA), Universiteitsplein 1, B-2610 Antwerp, Belgium.

C 26.Effect of octreotide on afferent responses during intestinal anaphylaxis. W. Jiang, D. Grundy. Dept. of Biomedical Science, University of Sheffield, Sheffield (UK)

C 27.Role of macrophage-colony stimulating factor-dependent macrophages in inflammation-induced deficit of enteric cholinergic nerve function. F. Galeazzi, P. Lovato, P.A. Blennerhasset, B.A. Vallance, S.M. Collins. Intestinal Disease Research Programme and GI Division, McMaster University, Hamilton (Canada) Dept. of Surgical and Gastroenterological Sciences, University of Padova, Padova (Italy)

C 28.Neuro-immune relationships in the colonic mucosa of irritable bowel syndrome patients. G. Barbara, V. Stanghellini, R. De Giorgio, L. Cogliandro, G. Pasquinelli, G. Cenacchi, D. Santini, F. Corradi, C. Cremon, B. Salvioli, R. Cogliandro, R. Corinaldesi. Depts. of Internal Medicine and Gastroenterology, Cytopathology and Pathology, University of Bologna, Bologna (Italy)

ORAL COMMUNICATIONS

Saturday, June 17

9.00-11.00

C 29.GLP-1(7-36)amide is a physiological inhibitory modulator of tonic and phasic motor activity of the gastric fundus. J. Schirra, M. Nicolaus, C. Craney, U. Wank, R. Arnold, B. Göke, M. Katschinski. Depts. of Gastroenterology, Phillips University, Marburg (Germany) and Bern University, Bern (Switzerland)

C 30.Effect of fatty acid chain-length on fat induced changes in proximal gastric motor and sensory function in man. B. Mearadji, C.B.H.W. Lamers, A.A.M. Masclee. Dept. of Gastroenterology, Leiden University Medical Center, Leiden (The Netherlands)

C 31. Effect of meal volume on proximal and distal gastric accommodation; relation between gastric accommodation and sensations. M. Mundt, M. Samsom, T. Hausken, A.J.P.M. Smout. Gastrointestinal Research Unit, Depts. of Gastroenterology and Surgery, University Medical Center, Utrecht (The Netherlands)

C 32.Modulation of gastric motor activity by illusory self-motion (vection). H. Faas, P. Enck, P. Boesiger, C. Feinle. Biophysics Division, ETH Zürich, Zürich (Switzerland) University of Tübingen, Tübingen (Germany)

C 33.Role of vagal innervation on intragastric distribution and emptying of solids. S. Blat, S. Guérin, A. Chauvin, J. LeCloirec, P. Bourget, C.H. Malbert. Unité Mixte de Recherche sur le Veau et le Porc, INRA, Saint-Gilles (France)

C 34.GLP-1(7-36)amide inhibits tonic and phasic motor activity of the fundus and modulates gastric sensation. U. Wank, J. Schirra, R. Arnold, B. Göke, M. Katschinski. Depts. of Gastroenterology, Phillips University, Marburg (Germany) and Bern University, Bern (Switzerland) Laboratoire de Médecine Nucléaire, Centre Eugène Marquis, Rennes (France)

C 35.The relationship between symptom severity and pathophysiological abnormalities in functional dyspepsia. R. Bisschops, J. Tack, P. Caenepeel, T. Degreef, J. Janssens. Center for Gastroenterological Research, University of Leuven, Leuven (Belgium)

C 36.Impaired accommodation in functional dyspepsia: site of the defect. J. Tack, I. Demedts, T. Degreef, P. Caenepeel, J. Janssens. Center for Gastroenterological Research, University of Leuven, Leuven (Belgium)

ORAL COMMUNICATIONS

Saturday, June 17

15.00-16.30

C 37.Interdigestive small bowel motility and microflora in experimental acute pancreatitis. I.D. van Felius, A. Verheem, K. Bosscha, M.R. Visser, W. Harmsen, J.E. van Dijk, I. van de Gaag, L.M.A. Akkermans, H.G. Gooszen Depts. of Surgery and Microbiology, University Medical Center and Dept. of Pathology, Veterinary Faculty, Utrecht University, Utrecht (The Netherlands)

C 38.Small bowel wall and luminal variations in response to a nutrient meal. N. Pallotta, E. Calabrese, E. Corazziari. Dipartimento Scienze Cliniche, Gastroenterologia I, Università "La Sapienza", Roma (Italy)

C 39.Differential regulation of postprandial jejunal motility and transit by endogenous CCK and cholinergic neural input. . Katschinski, U. Wank, J. Schirra, R. Arnold, B. Göke. Depts. of Gastroenterology, Phillips University, Marburg (Germany) and Bern University, Bern (Switzerland)

C 40.Effect of adenosine on neuronally mediated contractions in normal and in chronically inflamed ileum of the mouse. J.G. De Man, T.C. Seerden, T.G. Moreels, B.Y. De Winter, J.J. Bogers, E.A. Van Marck, A.G. Herman, P.A. Pelckmans. Divs. of Gastroenterology, Pathology and Pharmacology, University of Antwerp, Antwerp (Belgium)

C 41.Lymphocyte subsets and chemokine expression in idiopathic myenteric ganglionitis (IMG). R. De Giorgio, G. Barbara, V. Stanghellini, L. Pulsatelli, P. Dolzani, R. Meliconi, M. Benedikter, A. Facchini, S.M. Collins, R. Corinaldesi. Dept. of Internal Medicine and Gastroenterology, and Immunology Laboratory IOR, University of Bologna, Bologna (Italy) IDRP, McMaster University, Hamilton (Canada)

C 42.Proximal gastrointestinal and gallbladder motility after colectomy with pouch reconstruction. J. Steens, U.G. Schlüter, M.K. Vu, W.A. Bemelman, G. Griffioen, R.A. van Hogezand, C.B.H.W. Lamers, A.A.M. Masclee. Depts. of Gastroenterology and Surgery, Leiden University Medical Center, Leiden (The Netherlands) Amsterdam Medical Center, Amsterdam (The Netherlands)

POSTER VIEWING

Thursday, June 15

13.00-14.30

P 1.Defective vagal function in patients with prior antireflux surgery

P 2.Effect of solid bolus consistency and volume on pharyngeal transit assessed by acoustic technique

P 3.Prolonged manometric recordings of esophagus and lower esophageal sphincter in achalasia patients

P 4.Does intragastric PH influence lower esophageal sphincter motor function?

P 5.Effects of specific activation of esophageal versus gastroduodenal thermoreceptors on gastric emptying

P 6.Effect of sildenafil on esophageal motility

P 7.Criteria improving the diagnosis of gastroesophageal reflux (GOR) in patients with unexplained respiratory and oropharingeal symptoms

P 8.The functional pharingoesophagogastroscopy: a new technique

P 9.Effect of sildenafil, a phosphodiasterase 5 inhibitor, on esophageal motility in cats

P 10.Effects of sildenafil on antroduodenal motility

P 11.Impaired gastric accommodation in patients with alcoholic liver cirrhosis

P 12.Delayed gastric emptying is mainly related to fecal stasis in chronic constipated patients

P 13.Nausea-induced alterations in olfactory sensitivity are determined by stress hormones

P 14.Autonomic dysfunction in hyperthyroid patients affects gastric mioelectrical activity and emptying

P 15.The nitric oxide synthase inhibitor L-NMMA inhibits the accommodation reflex and induces early satiety in man

P 16.Microchip (MC) controlled short-term food intake in rats. Preliminary results

P 17.Postprandial vagal control of insulin secretion in conscious pigs

P 18.Effects of cholecystectomy on duodeno-jejunal (DJ) motility: a prospective study with a comparison between symptomatic (SP) and asymptomatic (ASP) patients

P 19.Effect of serotonin and ondansetron on upper GI manometry in healthy volunteers

P 20.Unhydrolysed proteins stimulate ileal motility whereas partially hydrolysed ones are inhibitory

P 21.Electrical conduction of spontaneous peristaltic waves in the feline duodenum

P 22.Two-dimensional motility mapping of the isolated feline duodenum: initial results

P 23.Effect of treatment with recombinant human IL-11(rhIL-11) on peptide and peptide receptor levels in normal rabbits

P 24.Effects of generalized hypothermia and re-warming on gastric emptying and gastro-duodenal motility in anaesthetized pigs

P 25.Colonic smooth muscle responses in patients with diverticular disease of the colon

P 26.Specific challenge enhances rectal sensitivity to distension in patients with food allergy

P 28.Rectal compliance and perception after faecal diversion

P 27.Transdermal nicotine decreased visceral perception in patients with diarrhea-predominant irritable bowel syndrome

P 28.Rectal compliance and perception after faecal diversion

P 29.Modulation of the spontaneous motility in rat colon: role for endogenous tachykinins

P 30.Increased calcium influx in proximal colon of dystrophic mice

P 31.Should the barium swallow be part of GERD work-up?

P 32.The relevance of the permanent intrathoracic axial migration of the GEJ in GERD

P 33.No differences in esophageal motility using a 21-channel system between patients with and without intestinal metaplasia at the esophagogastric junction

P 34.Twenty-four-hour esophageal motility testing in the clinical practice: a critical evaluation

P 35.Manofluorography: proposal of a prototype apparatus with manometric balloon sensors for the study of the pharyngo-esophageal tract

P 36.Role of videotapefluorography in the study of esophageal motility disorders (EMD)

P 37.Post-operative function of "ileo-colic free auograft" for replacement of the airway and upper digestive tract

P 38.Effect of clarithromycin on esophageal motility

P 39.Dyspeptic symptoms include frequent belching, headache and drowsiness but none of them is associated with delayed gastric emptying

P 40.Proximal and distal gastric accommodation in response to a liquid nutrient; effect of an intragastric bag on antral accommodation

P 41.Reproducibility of a drink test to study visceral hypersensitivity

P 42.Measurement of gastric emptying using ¹³C-octanoic acid breath test: which dose, test duration and mathematical model is best?

P 43.Lap band® is the treatment of choice for obese patients with gastroesophageal reflux disease (GERD)

P 44.Clarithromycin accelerates gastric emptying by inducing powerful antral contractions

P 45.Acute effect of alcohol on gastric emptying and intestinal transit in alcohol-naïve and chronic alcohol treated rats

P 46.Effect of isosorbide dinitrate on gastric relaxation after fundoplication in conscious rat

P 47.Effects of Neurotrophin 3 (NT3) on gastric and small intestinal motility in awake rats

P 48.Sphincter of Oddi manometry: what medication is appropriate?

P 49.Does gallbladder motility relate to biliary symptom frequency in cholesterol gallstone patients?

P 50.Changes of electrical activity of smooth muscles of intestinal wall in impaired circulatory function

P 51.The abdominal compartment syndrome following peritonitis and myoelectrical activity of the small bowel

P 52.The influence of nitric oxide on nitric oxide synthetising myenteric neurons

P 53.Role of nitric oxide in the regulation of migrating myoelectric complex in sheep

P 54.Assessment of intestinal motor responsiveness in an ischemia/reperfusion model in rats

P 55.Visceral hypersensitivity is not a feature of fibromyalgia syndrome

P 56.Efficacy of pinaverium bromide in Irritable Bowel Syndrome (IBS): differences between responders and non-responders

P 57.Pelvic-floor rehabilitation: benefit and long-term follow-up in idiophatic constipation

P 58.Spectral characteristics of the motor activity of the interposed colonic segment after esophagectomy

P 59.Nitrergic neurotransmission mediated relaxations of rat proximal colon is diminished in late pregnancy

P 60.Selective 5-HT₄ agonists affect 5-HT-induced contractions in guinea-pig colon to a different extent

P 61.Ineffective esophageal motility (IEM): a primary motility disorder

P 62.Chest pain and gender in nutcracker esophagus

P 63.HP infection and eradication does not influence symptoms and reflux pattern in GERD

P 64.Prevalence of, and role of gastroesophageal reflux in functional heartburn

P 65.Psychological assessment of patients with gastro-esophageal reflux (GERD)

P 66.Long-term evaluation of the patient's grade of satisfaction after surgical therapy for GERD

P 67.Gastric myoelectric activity in cardiac syndrome X patients

P 68.Gastric myoelectric activity and emptying in autonomic dysfunctions diabetic patients

P 69.Simplified evaluation of gastric sensitivity: latex balloon or polyethylene bag?

P 70.Formation of peg-and-socket junction

P 71.Postprandial small bowel motility in adult patients with Hirschsprung’s disease

P 72.Circadian variation of phase III contractions of the jejunal migrating motor complex

P 73.Different effect of endogenous opioids on d- and µ-receptors in the concious dog upper small intestine

P 74.Presence of a functional motilin receptor in TE671 cells from human cerebellum

P 75.Neural mechanisms related to inhibition of gastrointestinal motility in awake rats due to thoracic spinal cord transection

P 76.The role of nitric oxide on endotoxin-induced ileus and mortality in mice

P 77.Neostigmine effect on colonic motility in normal volunteers and postoperative patients

P 78.Gender but not age influence anorectal manometry (ARM) values in healthy controls